Using Freshdesk, you can send an auto-response notification for Out Of Office or after Business Hours. To meet this requirement, set up an automation rule under Admin > Workflows > Automations > Ticket creation > New rule.

Sample rule:


In tickets > If Created > During > Non-Business Hours > specify the business hours


Send Email to requester (customize the Subject and Body)

You can also reorder the rules you've added as described in the below video: